Since OS X 10.4.9 (that includes 10.4.10/10.4.11/10.5.x/.) many users have been experiencing that one button press on their remote does now trigger two reactions - once from any currently running application that supports the Apple® Remote, once the default system action. If that summary was too short, here's some more info on each of the points:
The Setup Wizard already contains a summary on how the driver does help Remote Buddy to provide additional features and hardware support.